NAV

Bamipine

This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Bamipineis an H1 antihistamine used topically to relieve mild to moderate symptoms associated with insect bites.

创eric Name
Bamipine
DrugBank Accession Number
DB13489
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
 3D
Similar Structures
Weight
Average: 280.415
Monoisotopic: 280.193948781
Chemical Formula
C19H24N2
Synonyms
  • Bamipine

Pharmacology

Indication

Not Available

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Associated Conditions
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRsBrowse all" title="" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

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This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction
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Hyoscyamine Bamipine may increase the anticholinergic activities of Hyoscyamine.
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Food Interactions
Not Available

Products

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Categories

ATC Codes
R06AX01 — Bamipine D04AA15 — Bamipine
Drug Categories
Chemical TaxonomyProvided byClassyfire
Description
This compound belongs to the class of organic compounds known as phenylbenzamines. These are aromatic compounds consisting of a benzyl group that is N-linked to a benzamine.
Kingdom
Organic compounds
Super Class
苯环型的
Class
Benzene and substituted derivatives
Sub Class
Phenylmethylamines
Direct Parent
Phenylbenzamines
Alternative Parents
Dialkylarylamines/Benzylamines/Aniline and substituted anilines/Aralkylamines/Aminopiperidines/三烷基胺/Azacyclic compounds/Organopnictogen compounds/Hydrocarbon derivatives
Substituents
4-aminopiperidine/Amine/Aniline or substituted anilines/Aralkylamine/Aromatic heteromonocyclic compound/Azacycle/Benzylamine/Dialkylarylamine/Hydrocarbon derivative/Organic nitrogen compound
Molecular Framework
Aromatic heteromonocyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
Y6BHZ28O92
CAS number
4945-47-5
InChI Key
VZSXTYKGYWISGQ-UHFFFAOYSA-N
InChI
InChI=1S/C19H24N2/c1-20-14-12-19(13-15-20)21(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17/h2-11,19H,12-16H2,1H3
IUPAC Name
N-benzyl-1-methyl-N-phenylpiperidin-4-amine
SMILES
CN1CCC(CC1)N(CC1=CC=CC=C1)C1=CC=CC=C1

References

创eral References
  1. DIMDI Drug Product Information: Soventol (bamipine) topical gel [Link]
ChemSpider
65061
RxNav
18753
ChEBI
135165
ChEMBL
CHEMBL520400
ZINC
ZINC000000000987
Wikipedia
Bamipine

Clinical Trials

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Phase Status Purpose Conditions Count

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Form Route Strength
Gel Topical 20 mg/g
Gel Topical 20 mg
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Property Value Source
Water Solubility 0.0434 mg/mL ALOGPS
logP 3.96 ALOGPS
logP 3.83 Chemaxon
logS -3.8 ALOGPS
pKa (Strongest Basic) 8.76 Chemaxon
Physiological Charge 1 Chemaxon
Hydrogen Acceptor Count 2 Chemaxon
Hydrogen Donor Count 0 Chemaxon
Polar Surface Area 6.48 Å2 Chemaxon
Rotatable Bond Count 4 Chemaxon
Refractivity 90.55 m3·mol-1 Chemaxon
极化率 33.15 Å3 Chemaxon
Number of Rings 3 Chemaxon
Bioavailability 1 Chemaxon
Rule of Five Yes Chemaxon
Ghose Filter Yes Chemaxon
Veber's Rule Yes Chemaxon
MDDR-like Rule No Chemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Spectrum Spectrum Type Splash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available

Drug created at June 23, 2017 20:43 / Updated at May 07, 2021 21:08