NAV

Diazolidinylurea

This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Diazolidinylureais an ingredient used in hospitals for disinfection.

Generic Name
Diazolidinylurea
DrugBank Accession Number
DB14173
Background

Not Available

Type
Small Molecule
Groups
Approved, Experimental
Structure
 3D
Similar Structures
Weight
Average: 278.2194
Monoisotopic: 278.086248822
Chemical Formula
C8H14N4O7
Synonyms
  • Diazolidinyl urea
  • N-(1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-N,N'-bis(hydroxymethyl)urea
  • N,N'-Bis(hydroxymethyl) urea

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Associated Conditions
Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug events
Improve clinical decision support with information oncontraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including:blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRsBrowse all" title="" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug InteractionsLearn More" title="" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image
Medi Fect Antiseptic Hand Wash Diazolidinylurea(1 g/100mL)+Ethanol(59.86 g/100mL) Liquid Topical Medical Chemical Corporation 2001-05-14 Not applicable US flag
SpectraGenix Hand Sanitizer Antiseptic Hand Wash Diazolidinylurea(0.167 g/100mL)+Ethanol(55.34 g/100mL) Liquid Topical Medical Chemical Corporation 2020-10-23 Not applicable US flag
T.R.U.E. Test Thin-Layer Rapid Use Patch Test Diazolidinylurea(446 ug/48h)+2,2'-Dibenzothiazyl disulfide(20 ug/48h)+2-mercaptobenzothiazole(61 ug/48h)+4-(Isopropylamino)diphenylamine(10 ug/48h)+Bacitracin(486 ug/48h)+Balsam of Peru(648 ug/48h)+Benzocaine(378 ug/48h)+Benzylparaben(162 ug/48h)+Bisphenol A diglycidyl ether(32 ug/48h)+Bromothalonil(4 ug/48h)+Bronopol(203 ug/48h)+Budesonide(0.8 ug/48h)+Butylparaben(162 ug/48h)+Chlorquinaldol(77 ug/48h)+Cinchocaine hydrochloride(66 ug/48h)+Cinnamaldehyde(41 ug/48h)+Cinnamyl alcohol(63 ug/48h)+Clioquinol(77 ug/48h)+Cobalt chloride hexahydrate(4 ug/48h)+Potassium dichromate(15.7 ug/48h)+Dipentamethylenethiuram disulfide(5.5 ug/48h)+Diphenylguanidine(68 ug/48h)+分散蓝106(41 ug/48h)+Disulfiram(5.5 ug/48h)+Ditiocarb zinc(68 ug/48h)+Ethyl hydroxybenzoate(162 ug/48h)+Ethylenediamine(18 ug/48h)+Eugenol(41 ug/48h)+Evernia prunastri(81 ug/48h)+Formaldehyde(146 ug/48h)+Geraniol(81 ug/48h)+Hydrocortisone butyrate(16 ug/48h)+Hydroxycitronellal(63 ug/48h)+Imidurea(486 ug/48h)+Isoeugenol(17 ug/48h)+Lanolin alcohols(810 ug/48h)+Methylchloroisothiazolinone(3 ug/48h)+Methylparaben(162 ug/48h)+Morpholinylmercaptobenzothiazole(20 ug/48h)+N,N'-diphenyl-1,4-phenylenediamine(25 ug/48h)+N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine(25 ug/48h)+Neomycin sulfate(486 ug/48h)+Nickel sulfate hexahydrate(36 ug/48h)+Parthenolide(2 ug/48h)+Propylparaben(162 ug/48h)+Quaternium-15(81 ug/48h)+Rosin(972 ug/48h)+Sodium aurotiosulfate(23 ug/48h)+Tetracaine hydrochloride(66 ug/48h)+Tetramethylthiuram monosulfide(5.5 ug/48h)+Thimerosal(6 ug/48h)+Thiohexam(20 ug/48h)+Thiram(5.5 ug/48h)+Tixocortol pivalate(2 ug/48h)+Zinc dibutyldithiocarbamate(68 ug/48h)+alpha-Amyl cinnamaldehyde(17 ug/48h)+p-Phenylenediamine(65 ug/48h)+p-tert-Butylphenol-formaldehyde resin (low molecular weight)(36 ug/48h) Kit Cutaneous SmartPractice Denmark ApS 2012-03-01 Not applicable US flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
N9VX1IBW6K
CAS number
78491-02-8
InChI Key
SOROIESOUPGGFO-UHFFFAOYSA-N
InChI
InChI=1S/C8H14N4O7/c13-1-9-7(18)10(2-14)5-6(17)12(4-16)8(19)11(5)3-15/h5,13-16H,1-4H2,(H,9,18)
IUPAC Name
1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea
SMILES
OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O

References

General References
Not Available
ChemSpider
56078
RxNav
1310602
ChEBI
136014
ChEMBL
CHEMBL3187032
Wikipedia
Diazolidinyl_urea

Clinical Trials

Clinical TrialsLearn More" title="" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count

Pharmacoeconomics

制造商
Not Available
Packagers
Not Available
Dosage Forms
Form Route Strength
Liquid Topical
Kit Cutaneous
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Property Value Source
Water Solubility 29.1 mg/mL ALOGPS
logP -2.2 ALOGPS
logP -3.8 Chemaxon
logS -0.98 ALOGPS
pKa (Strongest Acidic) 12.58 Chemaxon
pKa (Strongest Basic) -3 Chemaxon
Physiological Charge 0 Chemaxon
Hydrogen Acceptor Count 7 Chemaxon
Hydrogen Donor Count 5 Chemaxon
Polar Surface Area 153.88 Å2 Chemaxon
Rotatable Bond Count 5 Chemaxon
Refractivity 56.02 m3·mol-1 Chemaxon
Polarizability 24.29 Å3 Chemaxon
Number of Rings 1 Chemaxon
Bioavailability 1 Chemaxon
Rule of Five Yes Chemaxon
Ghose Filter No Chemaxon
Veber's Rule No Chemaxon
MDDR-like Rule No Chemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Spectrum Spectrum Type Splash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available

Drug created at June 29, 2018 22:16 / Updated at June 12, 2020 16:53