Steroids, Fluorinated

Name
Steroids, Fluorinated
Accession Number
DBCAT000749
Description

Steroids which are substituted with one or more fluorine atoms in any position.

Drugs
Drug Drug Description
Diflorasone A topical corticosteroid used to treat the symptoms of various inflammatory skin conditions that cause erythema, pruritus, and discomfort.
Amcinonide A topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.
Betamethasone A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Desoximetasone A glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Fluocinolone acetonide A corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye.
Ulobetasol A lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Triamcinolone A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
Flumethasone A corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions.
Flurandrenolide A corticosteroid used to treat corticosteroid-responsive dermatoses.
Clobetasol propionate A corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis.
Fluocinonide A high potency corticosteroid commonly used topically for a number of inflammatory skin conditions.
Dexamethasone A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Paramethasone For the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary...
Difluprednate A topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery.
Fluocortolone A glucocorticoid used topically for localized skin reactions and also orally for systemic use.
Difluocortolone A topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.
Clobetasone A corticosteroid used to treat dry eyes, eczema, and dermatitis.
Betamethasone phosphate A fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions.
Fluocortolone pivalate A corticosteroid used to treat corticosteroid-responsive dermatoses and hemorrhoids.
Fluocortolone caproate A corticosteroid indicated in the treatment of hemorrhoids, anal fissures, and corticosteroid-responsive dermatoses.
Fluorometholone An ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye.
Fluoxymesterone A synthetic androgenic anabolic steroid that used in the treatment of hypogonadism and delayed puberty in males, as well as breast neoplasms in women.
Fluprednisolone A synthetic glucocorticoid with anti-inflammatory properties.
Halometasone A corticosteroid indicated in the treatment of corticosteroid responsive dermatoses.
Flunisolide An inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
Clocortolone A corticosteroid used to treat inflammatory and pruritic dermatoses of the scalp.
Dexamethasone isonicotinate Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.
Isoflupredone Not Annotated
Clobetasol 应用氯倍他索正在调查中t of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.
Fluocinolone Fluocinolone has been used in trials studying the treatment and prevention of Candida Infection, Oral Lichen Planus, Macular Degeneration, and Choroidal Neovascularization.
Isoflupredone acetate Not Annotated
Dexamethasone acetate Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
Clocortolone acetate Not Annotated
Paramethasone acetate Not Annotated
Flunisolide acetate Not Annotated
Dexamethasone metasulfobenzoate An ophthalmic and auricular corticosteroid used with antibiotics for the treatment of otitis externa, blepharitis, and other inflammatory eye conditions.
Drugs & Drug Targets
Drug Target Type
Diflorasone Glucocorticoid receptor target
Amcinonide Glucocorticoid receptor target
Amcinonide Annexin A1 target
Amcinonide Cytochrome P450 3A4 enzyme
Amcinonide Cytochrome P450 3A5 enzyme
Betamethasone Glucocorticoid receptor target
Betamethasone Cytochrome P450 3A4 enzyme
Betamethasone P-glycoprotein 1 transporter
Betamethasone Cytochrome P450 19A1 enzyme
Betamethasone Cytochrome P450 3A5 enzyme
Betamethasone Cytochrome P450 3A7 enzyme
Betamethasone Cytochrome P450 2A6 enzyme
Betamethasone Cytochrome P450 1B1 enzyme
Betamethasone Cytochrome P450 2B6 enzyme
Betamethasone Cytochrome P450 2C8 enzyme
Betamethasone Cytochrome P450 2C9 enzyme
Betamethasone Cytochrome P450 2C19 enzyme
Betamethasone Serum albumin carrier
Betamethasone Corticosteroid-binding globulin carrier
Desoximetasone Glucocorticoid receptor target
Fluocinolone acetonide Corticosteroid-binding globulin carrier
Fluocinolone acetonide Glucocorticoid receptor target
Fluocinolone acetonide Cytochrome P450 3A4 enzyme
Fluocinolone acetonide Annexin A1 target
Fluocinolone acetonide Annexin A2 target
Fluocinolone acetonide Annexin A3 target
Fluocinolone acetonide Annexin A4 target
Fluocinolone acetonide Annexin A5 target
Fluocinolone acetonide Phospholipase A2 target
Ulobetasol Corticosteroid-binding globulin carrier
Ulobetasol Glucocorticoid receptor target
Triamcinolone Corticosteroid-binding globulin carrier
Triamcinolone Glucocorticoid receptor target
Triamcinolone Cytochrome P450 3A4 enzyme
Triamcinolone Prostaglandin G/H synthase 2 enzyme
Triamcinolone Cholinesterase enzyme
Triamcinolone Cytochrome P450 3A5 enzyme
Triamcinolone Cytochrome P450 3A7 enzyme
Triamcinolone Serum albumin carrier
Flumethasone Corticosteroid-binding globulin carrier
Flumethasone Glucocorticoid receptor target
Flumethasone Cytochrome P450 3A4 enzyme
Flurandrenolide Corticosteroid-binding globulin carrier
Flurandrenolide Glucocorticoid receptor target
Flurandrenolide Cytochrome P450 3A4 enzyme
Clobetasol propionate Glucocorticoid receptor target
Clobetasol propionate Cytochrome P450 3A4 enzyme
Clobetasol propionate Cytochrome P450 3A5 enzyme
Clobetasol propionate Annexin A1 target
Clobetasol propionate Mineralocorticoid receptor target
Clobetasol propionate Corticosteroid-binding globulin carrier
Clobetasol propionate Serum albumin carrier
Fluocinonide Corticosteroid-binding globulin carrier
Fluocinonide Glucocorticoid receptor target
Fluocinonide Smoothened homolog target
Fluocinonide Cytochrome P450 3A4 enzyme
Fluocinonide Cytochrome P450 3A5 enzyme
Dexamethasone Glucocorticoid receptor target
Dexamethasone Annexin A1 target
Dexamethasone Nitric oxide synthase, inducible target
Dexamethasone Nuclear receptor subfamily 0 group B member 1 target
Dexamethasone Cytochrome P450 3A4 enzyme
Dexamethasone Cytochrome P450 3A5 enzyme
Dexamethasone Cytochrome P450 3A7 enzyme
Dexamethasone Bile salt export pump transporter
Dexamethasone P-glycoprotein 1 transporter
Dexamethasone Canalicular multispecific organic anion transporter 1 transporter
Dexamethasone Solute carrier organic anion transporter family member 1A2 transporter
Dexamethasone ATP-binding cassette sub-family G member 2 transporter
Dexamethasone Steroid 17-alpha-hydroxylase/17,20 lyase enzyme
Dexamethasone Cytochrome P450 1A1 enzyme
Dexamethasone Cytochrome P450 2A6 enzyme
Dexamethasone Cytochrome P450 2B6 enzyme
Dexamethasone Cytochrome P450 2C19 enzyme
Dexamethasone Cytochrome P450 2C8 enzyme
Dexamethasone Cytochrome P450 2E1 enzyme
Dexamethasone Cytochrome P450 3A43 enzyme
Dexamethasone Cytochrome P450 4A11 enzyme
Dexamethasone Nuclear receptor subfamily 1 group I member 2 target
Dexamethasone 线粒体细胞色素P450 11 b1 enzyme
Dexamethasone Serum albumin carrier
Dexamethasone Corticosteroid 11-beta-dehydrogenase isozyme 2 enzyme
Dexamethasone Corticosteroid 11-beta-dehydrogenase isozyme 1 enzyme
Dexamethasone Solute carrier family 22 member 8 transporter
Paramethasone Corticosteroid-binding globulin carrier
Paramethasone Glucocorticoid receptor target
Paramethasone Cytochrome P450 3A4 enzyme
Paramethasone Cytochrome P450 3A5 enzyme
Difluprednate Glucocorticoid receptor target
Difluprednate Cytochrome P450 3A4 enzyme
Fluocortolone Cytochrome P450 3A4 enzyme
Fluocortolone Cytochrome P450 3A5 enzyme
Difluocortolone Annexin A3 target
Difluocortolone Glucocorticoid receptor target
Difluocortolone Cytochrome P450 3A4 enzyme
Difluocortolone Cytochrome P450 3A5 enzyme
Clobetasone Glucocorticoid receptor target
Clobetasone Cytochrome P450 3A4 enzyme
Betamethasone phosphate Cytochrome P450 3A4 enzyme
Betamethasone phosphate Cytochrome P450 3A5 enzyme
Betamethasone phosphate Glucocorticoid receptor target
Betamethasone phosphate Annexin A1 target
Betamethasone phosphate Corticosteroid-binding globulin carrier
Betamethasone phosphate Serum albumin carrier
Betamethasone phosphate Solute carrier organic anion transporter family member 1A2 transporter
Betamethasone phosphate P-glycoprotein 1 transporter
Betamethasone phosphate Solute carrier family 22 member 8 transporter
Fluorometholone Corticosteroid-binding globulin carrier
Fluorometholone Cytochrome P450 3A4 enzyme
Fluorometholone Glucocorticoid receptor target
Fluorometholone Cytochrome P450 3A5 enzyme
Fluoxymesterone Sex hormone-binding globulin carrier
Fluoxymesterone Estrogen receptor alpha target
Fluoxymesterone Androgen receptor target
Fluoxymesterone Glucocorticoid receptor target
Fluoxymesterone Corticosteroid 11-beta-dehydrogenase isozyme 2 target
Fluprednisolone Cytochrome P450 3A4 enzyme
Halometasone Cytochrome P450 3A4 enzyme
Halometasone Cytochrome P450 3A5 enzyme
Flunisolide Corticosteroid-binding globulin carrier
Flunisolide Glucocorticoid receptor target
Flunisolide Cytochrome P450 3A4 enzyme
Clocortolone Glucocorticoid receptor target
Dexamethasone isonicotinate Cytochrome P450 3A4 enzyme
Dexamethasone isonicotinate Cytochrome P450 3A5 enzyme
Clobetasol Cytochrome P450 3A4 enzyme
Clobetasol Cytochrome P450 3A5 enzyme
Dexamethasone acetate Glucocorticoid receptor target
Dexamethasone acetate Annexin A1 target
Dexamethasone acetate Nitric oxide synthase, inducible target
Dexamethasone acetate Nuclear receptor subfamily 0 group B member 1 target
Dexamethasone acetate Cytochrome P450 3A4 enzyme
Dexamethasone acetate Cytochrome P450 3A5 enzyme
Dexamethasone acetate Cytochrome P450 3A7 enzyme
Dexamethasone acetate Bile salt export pump transporter
Dexamethasone acetate P-glycoprotein 1 transporter
Dexamethasone acetate Canalicular multispecific organic anion transporter 1 transporter
Dexamethasone acetate Solute carrier organic anion transporter family member 1A2 transporter
Dexamethasone acetate ATP-binding cassette sub-family G member 2 transporter
Dexamethasone acetate Steroid 17-alpha-hydroxylase/17,20 lyase enzyme
Dexamethasone acetate Cytochrome P450 1A1 enzyme
Dexamethasone acetate Cytochrome P450 2A6 enzyme
Dexamethasone acetate Cytochrome P450 2B6 enzyme
Dexamethasone acetate Cytochrome P450 2C19 enzyme
Dexamethasone acetate Cytochrome P450 2C8 enzyme
Dexamethasone acetate Cytochrome P450 2E1 enzyme
Dexamethasone acetate Cytochrome P450 3A43 enzyme
Dexamethasone acetate Cytochrome P450 4A11 enzyme
Dexamethasone acetate Nuclear receptor subfamily 1 group I member 2 target
Dexamethasone acetate 线粒体细胞色素P450 11 b1 enzyme
Dexamethasone acetate Serum albumin carrier
Dexamethasone acetate Corticosteroid 11-beta-dehydrogenase isozyme 2 enzyme
Dexamethasone acetate Corticosteroid 11-beta-dehydrogenase isozyme 1 enzyme
Dexamethasone acetate Solute carrier family 22 member 8 transporter
Clocortolone acetate Cytochrome P450 3A4 enzyme
Clocortolone acetate Cytochrome P450 3A5 enzyme