NAV

Butanilicaine

This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Butanilicaine
DrugBank Accession Number
DB13328
Background

Not Available

Type
Small Molecule
组
Experimental
Structure
 3D
Similar Structures
Weight
Average: 254.76
Monoisotopic: 254.1185909
Chemical Formula
C13H19ClN2O
Synonyms
  • 2-(Butylamino)-6'-chloro-o-acetoluidide
  • 2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide
  • 2-Butylamino-6'-chloro-o-acetotoluidide
  • Butacetoluide
  • Butanilicaina
  • Butanilicaine
  • Butanilicainum

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRsBrowse all" title="" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug InteractionsLearn More" title="" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction
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Abemaciclib The risk or severity of methemoglobinemia can be increased when Abemaciclib is combined with Butanilicaine.
Abiraterone The risk or severity of methemoglobinemia can be increased when Abiraterone is combined with Butanilicaine.
Acetaminophen The risk or severity of methemoglobinemia can be increased when Acetaminophen is combined with Butanilicaine.
Acetazolamide The risk or severity of methemoglobinemia can be increased when Acetazolamide is combined with Butanilicaine.
Acetic acid The risk or severity of methemoglobinemia can be increased when Acetic acid is combined with Butanilicaine.
Acetyl sulfisoxazole The risk or severity of methemoglobinemia can be increased when Acetyl sulfisoxazole is combined with Butanilicaine.
Adagrasib The risk or severity of methemoglobinemia can be increased when Adagrasib is combined with Butanilicaine.
Afatinib The risk or severity of methemoglobinemia can be increased when Afatinib is combined with Butanilicaine.
Aldesleukin The risk or severity of methemoglobinemia can be increased when Aldesleukin is combined with Butanilicaine.
Alectinib The risk or severity of methemoglobinemia can be increased when Alectinib is combined with Butanilicaine.
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Food Interactions
Not Available

Categories

ATC Codes
N01BB05 — Butanilicaine
Drug Categories
Chemical TaxonomyProvided byClassyfire
Description
This compound belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids.
Kingdom
Organic compounds
Super Class
Organic acids and derivatives
Class
Carboxylic acids and derivatives
Sub Class
Amino acids, peptides, and analogues
Direct Parent
Alpha amino acid amides
Alternative Parents
Anilides/N-arylamides/Toluenes/Chlorobenzenes/Aryl chlorides/Secondary carboxylic acid amides/Dialkylamines/Organopnictogen compounds/Organochlorides/Organic oxides
show 2 more
Substituents
Alpha-amino acid amide/Amine/Anilide/Aromatic homomonocyclic compound/Aryl chloride/Aryl halide/Benzenoid/Carbonyl group/甲酰胺组/Chlorobenzene
show 16 more
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
amino acid amide, monochlorobenzenes (CHEBI:55518)
Affected organisms
Not Available

Chemical Identifiers

UNII
7X3WV51F4N
CAS number
3785-21-5
InChI Key
VWYQKFLLGRBICZ-UHFFFAOYSA-N
InChI
InChI=1S/C13H19ClN2O/c1-3-4-8-15-9-12(17)16-13-10(2)6-5-7-11(13)14/h5-7,15H,3-4,8-9H2,1-2H3,(H,16,17)
IUPAC Name
2-(butylamino)-N-(2-chloro-6-methylphenyl)acetamide
SMILES
CCCCNCC(=O)NC1=C(C)C=CC=C1Cl

References

一般引用
Not Available
KEGG Drug
D07284
ChemSpider
21004
ChEBI
55518
ChEMBL
CHEMBL2104238
ZINC
ZINC000001841441
Wikipedia
Butanilicaine

Clinical Trials

Clinical TrialsLearn More" title="" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Property Value Source
Water Solubility 0.0665 mg/mL ALOGPS
logP 2.69 ALOGPS
logP 3.16 Chemaxon
logS -3.6 ALOGPS
pKa (Strongest Acidic) 12.3 Chemaxon
pKa (Strongest Basic) 8.69 Chemaxon
Physiological Charge 1 Chemaxon
Hydrogen Acceptor Count 2 Chemaxon
Hydrogen Donor Count 2 Chemaxon
Polar Surface Area 41.13 Å2 Chemaxon
Rotatable Bond Count 6 Chemaxon
Refractivity 72.77 m3·mol-1 Chemaxon
Polarizability 28.15 Å3 Chemaxon
Number of Rings 1 Chemaxon
Bioavailability 1 Chemaxon
Rule of Five Yes Chemaxon
Ghose Filter Yes Chemaxon
Veber's Rule No Chemaxon
MDDR-like规则 No Chemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Spectrum Spectrum Type Splash Key
Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available

Drug created at June 23, 2017 20:40 / Updated at February 21, 2021 18:54