This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Emetonium iodide
- DrugBank Accession Number
- DB13769
- Background
-
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
-
Structure for Emetonium iodide (DB13769)
- Weight
-
Average: 425.354
Monoisotopic: 425.12156 - Chemical Formula
- C20H28INO
- Synonyms
-
- (2-benzhydryloxyethyl)diethyl-methylammonium iodide
- Ethylbenzhydramine methyl iodide
Pharmacology
- Indication
-
Not Available
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Avoid life-threatening adverse drug eventsImprove clinical decision support with information oncontraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support. - Pharmacodynamics
-
Not Available
- Mechanism of action
- Not Available
- Absorption
-
Not Available
- Volume of distribution
-
Not Available
- Protein binding
-
Not Available
- Metabolism
- Not Available
- Route of elimination
-
Not Available
- Half-life
-
Not Available
- Clearance
-
Not Available
- Adverse Effects
-
Improve decision support & research outcomesWith structured adverse effects data, including:blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data. - Toxicity
-
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRsBrowse all" title="" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug InteractionsLearn More" title="" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
-
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAclidinium The risk or severity of adverse effects can be increased when Emetonium iodide is combined with Aclidinium. Adenosine The risk or severity of Tachycardia can be increased when Adenosine is combined with Emetonium iodide. Alfentanil The risk or severity of adverse effects can be increased when Emetonium iodide is combined with Alfentanil. Alloin The therapeutic efficacy of Alloin can be decreased when used in combination with Emetonium iodide. Amantadine The risk or severity of adverse effects can be increased when Amantadine is combined with Emetonium iodide. Ambenonium The therapeutic efficacy of Emetonium iodide can be decreased when used in combination with Ambenonium. Amitriptyline The risk or severity of adverse effects can be increased when Emetonium iodide is combined with Amitriptyline. Amitriptylinoxide The risk or severity of adverse effects can be increased when Emetonium iodide is combined with Amitriptylinoxide. Amobarbital The risk or severity of adverse effects can be increased when Amobarbital is combined with Emetonium iodide. Amoxapine The risk or severity of adverse effects can be increased when Emetonium iodide is combined with Amoxapine. 
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- Not Available
Products
-
Drug product information from 10+ global regionsOur datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions. - International/Other Brands
- Esyntin/Metropin
Categories
- ATC Codes
- A03AB16 — (2-benzhydryloxyethyl)diethyl-methylammonium iodide
- Drug Categories
- Chemical TaxonomyProvided byClassyfire
-
- 描述
- This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
- Kingdom
- Organic compounds
- Super Class
- Benzenoids
- Class
- Benzene and substituted derivatives
- Sub Class
- 二苯基甲烷s
- Direct Parent
- 二苯基甲烷s
- Alternative Parents
- Benzylethers/Tetraalkylammonium salts/Dialkyl ethers/Organopnictogen compounds/Organic iodide salts/Hydrocarbon derivatives/Amines
- Substituents
- Amine/Aromatic homomonocyclic compound/Benzylether/Dialkyl ether/二苯基甲烷/Ether/Hydrocarbon derivative/Organic iodide salt/Organic nitrogen compound/Organic oxygen compound
- Molecular Framework
- Aromatic homomonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
化学标识符
- UNII
- CW3OT0Y51W
- CAS number
- 5982-52-5
- InChI Key
- HKOZYKMXXBHEHT-UHFFFAOYSA-M
- InChI
-
InChI=1S/C20H28NO.HI/c1-4-21(3,5-2)16-17-22-20(18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,20H,4-5,16-17H2,1-3H3;1H/q+1;/p-1
- IUPAC Name
-
[2-(diphenylmethoxy)ethyl]diethylmethylazanium iodide
- SMILES
-
[I-].CC[N+](C)(CC)CCOC(C1=CC=CC=C1)C1=CC=CC=C1
References
- General References
- Not Available
- External Links
-
- ChemSpider
- 72334
- ChEMBL
- CHEMBL3707204
Clinical Trials
- Clinical TrialsLearn More" title="" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
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Phase Status Purpose Conditions Count
Pharmacoeconomics
- Manufacturers
-
Not Available
- Packagers
-
Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
-
Property Value Source Water Solubility 2.63e-05 mg/mL ALOGPS logP 0.41 ALOGPS logP 0.2 Chemaxon logS -7.2 ALOGPS pKa (Strongest Basic) -4.3 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 9.23 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 105.34 m3·mol-1 Chemaxon Polarizability 35.9 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
-
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available
Drug created at June 23, 2017 20:48 / Updated at June 12, 2020 16:53