一个tidiarrheals

Name
一个tidiarrheals
Accession Number
DBCAT001158 (DBCAT003732)
Description

Miscellaneous agents found useful in the symptomatic treatment of diarrhea. They have no effect on the agent(s) that cause diarrhea, but merely alleviate the condition.

Drugs
Drug Drug Description
Loperamide A long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis.
Diphenoxylate 一个antidiarrheal medication used with atropine to manage diarrhea.
Bismuth subsalicylate 一个antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
Kaolin A natural ingredient used for the short-term symptomatic treatment of various conditions including diarrhea, skin dryness, and minor skin bleeding.
Polycarbophil Polycarbophil is used to treat constipation and to help maintain regular bowel movements.
Carob 一个extract from Carob used in allergy testing.
Opium A medication used to treat moderate to severe pain.
Racecadotril 一个anti-secretory enkephalinase inhibitor useful in the treatment of diarrhea.
Difenoxin 一个antidiarrheal agent used as an adjunct for the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea.
Crofelemer 一个antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy.
Calcium polycarbophil A bulk forming laxative used to treat constipation.
Telotristat ethyl A tryptophan hydroxylase inhibitor that is used to treat carcinoid syndrome diarrhea.
Bismuth subgallate A medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery.
Loperamide oxide Not Annotated
Telotristat A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat.
Drugs & Drug Targets
Drug Target Type
Loperamide Voltage-dependent P/Q-type calcium channel subunit alpha-1A target
Loperamide Mu-type opioid receptor target
Loperamide Calmodulin target
Loperamide Pro-opiomelanocortin target
Loperamide Delta-type opioid receptor target
Loperamide Cytochrome P450 3A4 enzyme
Loperamide P-glycoprotein 1 transporter
Loperamide Kappa-type opioid receptor target
Loperamide Cytochrome P450 2C8 enzyme
Loperamide Cytochrome P450 2B6 enzyme
Loperamide Cytochrome P450 2D6 enzyme
Loperamide Potassium voltage-gated channel subfamily H member 2 target
Diphenoxylate Mu-type opioid receptor target
Diphenoxylate Delta-type opioid receptor target
Bismuth subsalicylate Serum albumin carrier
Bismuth subsalicylate Serotransferrin carrier
Opium Delta-type opioid receptor target
Opium Kappa-type opioid receptor target
Opium Mu-type opioid receptor target
Opium Serum albumin carrier
Opium Beta-2-microglobulin carrier
Opium Cytochrome P450 2D6 enzyme
Opium Cytochrome P450 3A4 enzyme
Crofelemer Cystic fibrosis transmembrane conductance regulator target
Crofelemer 一个octamin-1 target
Telotristat ethyl Tryptophan 5-hydroxylase 2 target
Telotristat ethyl Tryptophan 5-hydroxylase 1 target
Telotristat ethyl P-glycoprotein 1 transporter
Telotristat ethyl Cytochrome P450 3A4 enzyme
Telotristat ethyl Cytochrome P450 2B6 enzyme
Telotristat ethyl Liver carboxylesterase 1 enzyme
Telotristat ethyl ATP-binding cassette sub-family G member 2 carrier
Telotristat ethyl Cocaine esterase enzyme
Telotristat ethyl UDP-glucuronosyltransferase 2B4 enzyme
Telotristat ethyl UDP-glucuronosyltransferase 2B7 enzyme
Telotristat ethyl Cytochrome P450 2C9 enzyme
Telotristat ethyl Cytochrome P450 2C19 enzyme
Telotristat ethyl Cytochrome P450 2D6 enzyme
Telotristat ethyl Cytochrome P450 2C8 enzyme
Bismuth subgallate Serum albumin carrier