This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Aluminum oxide
- DrugBank Accession Number
- DB11342
- Background
-
Aluminum oxide has a chemical formula Al2O3. It is amphoteric in nature, and is used in various chemical, industrial and commercial applications. It is considered an indirect additive used in food contact substances by the FDA.
- Type
- Small Molecule
- Groups
- Approved
- Structure
-
Structure for Aluminum oxide (DB11342)
- Weight
-
Average: 101.96
Monoisotopic: 101.9478209 - Chemical Formula
- Al2O3
- Synonyms
-
- Aluminium oxide
Pharmacology
- Indication
-
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning models
with evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets. - Associated Conditions
- Contraindications & Blackbox Warnings
-
Avoid life-threatening adverse drug eventsImprove clinical decision support with information oncontraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support. - Pharmacodynamics
-
Not Available
- Mechanism of action
- Not Available
- Absorption
-
Not Available
- Volume of distribution
-
Not Available
- Protein binding
-
Not Available
- Metabolism
- Not Available
- Route of elimination
-
Not Available
- Half-life
-
Not Available
- Clearance
-
Not Available
- Adverse Effects
-
Improve decision support & research outcomesWith structured adverse effects data, including:blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data. - Toxicity
-
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRsBrowse all" title="" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- 药物的相互作用Learn More" title="" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
-
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareCarbamazepine Aluminum oxide can cause a decrease in the absorption of Carbamazepine resulting in a reduced serum concentration and potentially a decrease in efficacy. Chenodeoxycholic acid Aluminum oxide can cause a decrease in the absorption of Chenodeoxycholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy. Cholic Acid Aluminum oxide can cause a decrease in the absorption of Cholic Acid resulting in a reduced serum concentration and potentially a decrease in efficacy. Deferasirox Aluminum oxide can cause a decrease in the absorption of Deferasirox resulting in a reduced serum concentration and potentially a decrease in efficacy. Dehydrocholic acid Aluminum oxide can cause a decrease in the absorption of Dehydrocholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy. Deoxycholic acid Aluminum oxide can cause a decrease in the absorption of Deoxycholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy. Dolutegravir The serum concentration of Dolutegravir can be decreased when it is combined with Aluminum oxide. Eltrombopag Aluminum oxide can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy. Halofantrine Aluminum oxide can cause a decrease in the absorption of Halofantrine resulting in a reduced serum concentration and potentially a decrease in efficacy. Mephenytoin Aluminum oxide can cause a decrease in the absorption of Mephenytoin resulting in a reduced serum concentration and potentially a decrease in efficacy. 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- No interactions found.
Products
-
Drug product information from 10+ global regionsOur datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions. - Over the Counter Products
-
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image ALUMINIUM HYDROXIDE MIXTURE BP 4% w/w Suspension 4% w / w Oral SUNWARD PHARMACEUTICAL PRIVATE LIMITED 1989-04-21 Not applicable Singapore ALUTACID ANTACID MIXTURE 4% w/w Suspension 4% w / w Oral ICM PHARMA PTE. LTD. 1996-07-03 Not applicable Singapore Brasivol Fine Cream 38.2 % Topical Stiefel Laboratories, Inc. 1966-12-31 2000-01-07 Canada 
Brasivol Medium Cream 52.2 % Topical Stiefel Laboratories, Inc. 1966-12-31 2000-01-07 Canada Vfb Bio Peel Powder 6.5 mg/1g Topical General Bio Co., Ltd. 2014-12-09 2019-09-30 US 
- Mixture Products
-
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image POLGENTEC 2-120 GBQ GENERADOR DE RADIONUCLEIDOS Aluminum oxide(2 g)+Sodium molybdate(0 GBq)+Technetium Tc-99m sodium pertechnetate(120 GBq) Solution Intravenous ISOMEDIX TECHNOLOGY S.A.S. 2013-09-19 Not applicable Colombia 
- Unapproved/Other Products
-
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Vfb Bio Peel Aluminum oxide(6.5 mg/1g) Powder Topical General Bio Co., Ltd. 2014-12-09 2019-09-30 US
Categories
- ATC Codes
- D10AX04 — Aluminium oxide
- Drug Categories
- Chemical TaxonomyProvided byClassyfire
-
- Description
- This compound belongs to the class of inorganic compounds known as post-transition metal salts. These are inorganic halogenic compounds in which the heaviest metal atom is a post-transition metal.
- Kingdom
- Inorganic compounds
- Super Class
- Mixed metal/non-metal compounds
- Class
- Post-transition metal salts
- Sub Class
- Not Available
- Direct Parent
- Post-transition metal salts
- Alternative Parents
- Miscellaneous mixed metal/non-metals/Inorganic salts
- Substituents
- Inorganic post-transition metal salt/Inorganic salt/Miscellaneous mixed metal/non-metal
- Molecular Framework
- Not Available
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- LMI26O6933
- CAS number
- 1344-28-1
- InChI Key
- PNEYBMLMFCGWSK-UHFFFAOYSA-N
- InChI
-
InChI=1S/2Al.3O/q2*+3;3*-2
- IUPAC Name
-
dialuminium(3+) ion trioxidandiide
- SMILES
-
[O--].[O--].[O--].[Al+3].[Al+3]
References
- 一般引用
- Not Available
- External Links
-
- PubChem Compound
- 9989226
- PubChem Substance
- 347827970
- ChemSpider
- 8164808
- 615
- ChEMBL
- CHEMBL3707210
- Wikipedia
- Aluminium_oxide
Clinical Trials
- Clinical TrialsLearn More" title="" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
-
Phase Status Purpose Conditions Count
Pharmacoeconomics
- Manufacturers
-
Not Available
- Packagers
-
Not Available
- Dosage Forms
-
Form Route Strength Suspension Oral 4% w / w Cream Topical 38.2 % Cream Topical 52.2 % Solution Intravenous Powder Topical 6.5 mg/1g - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
-
Property Value Source logP -0.65 Chemaxon pKa (Strongest Acidic) 15.7 Chemaxon pKa (Strongest Basic) -1.8 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 13.11 m3·mol-1 Chemaxon Polarizability 0.95 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
-
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created at December 03, 2015 16:52 / Updated at May 21, 2021 10:22