This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Sulfaperin
- DrugBank Accession Number
- DB13320
- Background
-
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
-
Structure for Sulfaperin (DB13320)
- Weight
-
Average: 264.3
Monoisotopic: 264.068096816 - Chemical Formula
- C11H12N4O2S
- Synonyms
-
- Sulfaperin
- sulfaperina
Pharmacology
- Indication
-
Not Available
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with evidence-based and structured datasets.构建、培训和验证预测machine-learning models with structured datasets. - Contraindications & Blackbox Warnings
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Avoid life-threatening adverse drug eventsImprove clinical decision support with information oncontraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support. - Pharmacodynamics
-
Not Available
- Mechanism of action
- Not Available
- Absorption
-
Not Available
- Volume of distribution
-
Not Available
- Protein binding
-
Not Available
- Metabolism
- Not Available
- Route of elimination
-
Not Available
- Half-life
-
Not Available
- Clearance
-
Not Available
- Adverse Effects
-
Improve decision support & research outcomesWith structured adverse effects data, including:blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data. - Toxicity
-
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRsBrowse all" title="" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug InteractionsLearn More" title="" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
-
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Sulfaperin. Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Sulfaperin. Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfaperin. Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfaperin. Benzylpenicillin Sulfaperin may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level. Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Sulfaperin. Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Sulfaperin. Chloroprocaine The therapeutic efficacy of Sulfaperin can be decreased when used in combination with Chloroprocaine. Chlorpropamide Chlorpropa的治疗效果mide can be increased when used in combination with Sulfaperin. Cholestyramine Cholestyramine can cause a decrease in the absorption of Sulfaperin resulting in a reduced serum concentration and potentially a decrease in efficacy. 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Categories
- ATC Codes
- J01ED06 — Sulfaperin
- Drug Categories
- Chemical TaxonomyProvided byClassyfire
-
- Description
- This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
- Kingdom
- Organic compounds
- Super Class
- Benzenoids
- Class
- Benzene and substituted derivatives
- Sub Class
- Benzenesulfonamides
- Direct Parent
- Aminobenzenesulfonamides
- Alternative Parents
- Benzenesulfonyl compounds/Aniline and substituted anilines/Pyrimidines and pyrimidine derivatives/Organosulfonamides/Heteroaromatic compounds/Aminosulfonyl compounds/Azacyclic compounds/Primary amines/Organopnictogen compounds/Organic oxides show 1 more
- Substituents
- Amine/Aminobenzenesulfonamide/Aminosulfonyl compound/Aniline or substituted anilines/Aromatic heteromonocyclic compound/Azacycle/Benzenesulfonyl group/Heteroaromatic compound/Hydrocarbon derivative/Organic nitrogen compound show 12 more
- Molecular Framework
- Aromatic heteromonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- W5E840UV9P
- CAS number
- 599-88-2
- InChI Key
- DZQVFHSCSRACSX-UHFFFAOYSA-N
- InChI
-
InChI=1S/C11H12N4O2S/c1-8-6-13-11(14-7-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
- IUPAC Name
-
4-amino-N-(5-methylpyrimidin-2-yl)benzene-1-sulfonamide
- SMILES
-
CC1=CN=C(NS(=O)(=O)C2=CC=C(N)C=C2)N=C1
References
- General References
- Not Available
- External Links
-
- ChemSpider
- 62158
- ChEBI
- 131722
- ChEMBL
- CHEMBL2105499
- ZINC
- ZINC000000002102
- Wikipedia
- Sulfaperin
Clinical Trials
- Clinical TrialsLearn More" title="" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
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Phase Status Purpose Conditions Count
Pharmacoeconomics
- Manufacturers
-
Not Available
- Packagers
-
Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
-
Property Value Source Water Solubility 0.312 mg/mL ALOGPS logP 0.41 ALOGPS logP 0.9 Chemaxon logS -2.9 ALOGPS pKa (Strongest Acidic) 7.03 Chemaxon pKa (Strongest Basic) 2.02 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 97.97 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 69.24 m3·mol-1 Chemaxon Polarizability 25.96 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
-
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created at June 23, 2017 20:39 / Updated at February 21, 2021 18:54