Sulfamazone
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Identification
- Generic Name
- Sulfamazone
- DrugBank Accession Number
- DB13556
- Background
-
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
-
- Weight
-
平均:560.6
Monoisotopic: 560.114789485 - Chemical Formula
- C23H24N6O7S2
- Synonyms
-
- Sulfamazone
Pharmacology
- Indication
-
Not Available
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- Pharmacodynamics
-
Not Available
- Mechanism of action
- Not Available
- Absorption
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Not Available
- Volume of distribution
-
Not Available
- Protein binding
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Not Available
- Metabolism
- Not Available
- Route of elimination
-
Not Available
- Half-life
-
Not Available
- Clearance
-
Not Available
- Adverse Effects
-
Improve decision support & research outcomesWith structured adverse effects data, including:blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
-
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRsBrowse all" title="" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug InteractionsLearn More" title="" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
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This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Sulfamazone. Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Sulfamazone. Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfamazone. Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfamazone. Benzylpenicillin Sulfamazone may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level. Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Sulfamazone. Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Sulfamazone. Chloroprocaine The therapeutic efficacy of Sulfamazone can be decreased when used in combination with Chloroprocaine. Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Sulfamazone. Cholestyramine Cholestyramine can cause a decrease in the absorption of Sulfamazone resulting in a reduced serum concentration and potentially a decrease in efficacy. Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Products
-
Drug product information from 10+ global regionsOur datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
Categories
- ATC Codes
- J01ED09 — Sulfamazone
- Drug Categories
- Chemical TaxonomyProvided byClassyfire
-
- Description
- This compound belongs to the class of organic compounds known as phenylpyrazoles. These are compounds containing a phenylpyrazole skeleton, which consists of a pyrazole bound to a phenyl group.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Azoles
- Sub Class
- Pyrazoles
- Direct Parent
- Phenylpyrazoles
- Alternative Parents
- Benzenesulfonamides/Benzenesulfonyl compounds/Phenylalkylamines/Alkyl aryl ethers/Secondary alkylarylamines/Pyridazines and derivatives/Pyrazolones/Organosulfonamides/Imidolactams/Alkanesulfonic acids show 9 more
- Substituents
- Alkanesulfonic acid/Alkyl aryl ether/Amine/Aminosulfonyl compound/Aromatic heteromonocyclic compound/Azacycle/Benzenesulfonamide/Benzenesulfonyl group/Benzenoid/Ether show 24 more
- Molecular Framework
- Aromatic heteromonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- D7B8U8VA9J
- CAS number
- 65761-24-2
- InChI Key
- BGLHAKAJGYLSOX-UHFFFAOYSA-N
- InChI
-
InChI=1S/C23H24N6O7S2/c1-15-21(23(30)29(28(15)2)17-7-5-4-6-8-17)22(38(33,34)35)24-16-9-11-18(12-10-16)37(31,32)27-19-13-14-20(36-3)26-25-19/h4-14,22,24H,1-3H3,(H,25,27)(H,33,34,35)
- IUPAC Name
-
(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)({4-[(6-methoxypyridazin-3-yl)sulfamoyl]phenyl}amino)methanesulfonic acid
- SMILES
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COC1=CC=C(NS(=O)(=O)C2=CC=C(NC(C3=C(C)N(C)N(C3=O)C3=CC=CC=C3)S(O)(=O)=O)C=C2)N=N1
References
- 一般引用
- Not Available
- External Links
-
- ChemSpider
- 163211
- ChEBI
- 131763
- ChEMBL
- CHEMBL2104921
- Wikipedia
- Sulfamazone
Clinical Trials
- Clinical TrialsLearn More" title="" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
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Phase Status Purpose Conditions Count
Pharmacoeconomics
- Manufacturers
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Not Available
- Packagers
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Not Available
- Dosage Forms
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Form Route Strength Suppository Tablet - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
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Property Value Source Water Solubility 0.0389 mg/mL ALOGPS logP 1.61 ALOGPS logP -0.16 Chemaxon logS -4.2 ALOGPS pKa (Strongest Acidic) -1.6 Chemaxon pKa (Strongest Basic) -0.6 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 11 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 171.13 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 141.93 m3·mol-1 Chemaxon Polarizability 54.34 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like规则 Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
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Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created at June 23, 2017 20:44 / Updated at February 21, 2021 18:54